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New clinical research published in Cosmetics Journal has reinforced that Indian sandalwood oil is a powerful antioxidant and offers protection against blue light damage, after 2021 cellular research found it to be more potent than lipophilic antioxidant vitamin E (alpha tocopherol).

The study, commissioned by Quintis Sandalwood, is the first clinical trial proving that Indian sandalwood oil at a concentration between 1% and 10%, protects the skin against the oxidative stress induced by ambient dust and blue light exposure.

“The clinical trial reinforces our previous peer-reviewed cellular research, that found Indian sandalwood oil protects against oxidative stress in vitro. The result in vivo showed skin oxidation to be lower when treated with Indian sandalwood oil when compared to a-tocopherl,” explained Dhanushka Hettiarachchi, Ph.D., Technical Products Specialist for Quintis Sandalwood.

The results indicated that there was a dose-dependent decrease in the levels of free radical damage, with a concentration of Quintis Indian sandalwood (1%) representing a 24% decrease in Squalene monohydroperoxide (SQOOH) compared to non-treated study areas.

To evaluate the effects of Indian sandalwood oil on skin, the level of oxidised squalene was monitored as a measurement of skin oxidation. The study assessed the protective effect of a cosmetic product containing Indian sandalwood oil against cutaneous oxidative stress induced by environmental pollution such as ambient dust and blue light at a wavelength of 412 nm.

 “The detrimental impact of blue light in sunlight rays can have significant impact on skin pigmentation and skin ageing. Particles arising from ambient pollution can enter deeper layers of the skin, thereby inducing the release of free radicals and triggering an inflammatory cascade as well as skin barrier alteration,” said Hettiarachchi.

 “Many recent cosmetic trends have focused on retaining skin health and promoting positive ageing of skin when exposed to pollution and visible blue light from the sun. We are excited that this study further emphasises the power of Indian sandalwood oil in protecting the skin against environmental damage, further proving the multipurpose nature of this precious ingredient in cosmetics.”

To further the conversation on the role Indian sandalwood oil can play in enhancing overall skin health, Quintis is committed to continuing to invest in studies and trials to explore Indian sandalwood oil as a multipurpose highly effective antioxidant ingredient in cosmetics.

“Given these ongoing reinforced results, the benefits of Indian sandalwood oil are clear and there is a significant opportunity for cosmetic brand to consider incorporating Indian sandalwood oil into their formulations as a protective and anti-ageing active with multifunctionality ingredient in cosmetics and dermatology, opening up the potential to offer those benefits to consumers through a range of topical products.

“Quintis is passionate about demonstrating the positive impact Indian Sandalwood oil has on skin and continuing our research to better understand its benefits,” said Hettiarachchi.

Indian sandalwood oil is the essential oil obtained by steam distillation of the aromatic heartwood of Santalum album. In addition to its therapeutic benefits, the oil is renowned for its olfactory characteristics, having a soft, warm, and woody odour. As a result of this odour, the oil has found its way into many applications including perfumery, attars, and incense.

To read the manuscript in full, please click here.

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